The Department of Nematology started in 1977-78 at Anand campus of erstwhile Gujarat Agricultural University with one post each of Professor, Associate Professor and Assistant Professor. Late Prof. H. M. Shah was the first Professor and Head, Department of Nematology who initiated the work on Nematology. There after array of distinguished professors viz., Dr. D. J. Patel, Dr. N. A. Thakar, Dr. V. A. Patel, Dr. R. V. Vyas, Dr. B. N. Patel, Dr. J. G. Patel, Dr. B. A. Patel and Dr. A. B. Brahmabhatt adorned this chair. At present, Dr. R. K. Thumar is performing as Head of the Department. The All India Co-ordinated Research Project (AICRP) on Plant Parasitic Nematodes with Integrated Approach for Their Control was sanctioned on 7th April, 1977 at Anand campus of Gujarat Agricultural University and the project started functioning on 8th February, 1978.

The department is fully engaged in imparting quality education to the P. G and U. G. students in the form of teaching, research and extension. Besides this, research on management of nematode diseases in different economic crops grown in the state and extension activities are conducted to appraise the farmers about the nematode problems in the crops and their remedies. From 1977 to till date, main focus of research is to identify several nematode problems, mainly root-knot, reniform, cyst, stunt, burrowing and many other parasitic nematodes on various crops and evolved their economic management strategies for the farming community.